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BIG-PACK 40x Clomiphene citrate [50mg x 12 tabs]

Generic Name: clomiphene citrate

Clomiphene Citrate is typically prescribed for women to aid in ovulation. In men, the application of Clomid causes an elevation of follicle stimulating hormone and luteinizing hormone. As a result, natural testosterone production is also increased.

This effect is obviously beneficial to the athlete, especially at the conclusion of a steroid cycle when endogenous testosterone levels are subnormal. When an athlete discontinues the use of steroids, his testosterone levels will most likely be suppressed. If endogenous testosterone levels are not brought to normal, a dramatic loss in size and strength may occur. Clomid plays a crucial role in preventing this crash in athletic performance.

Bodybuilders find that a daily intake of 50-100 mg of clomiphene citrate over a two week period will bring endogenous testosterone production back to an acceptable level. Clomid will gradually raise testosterone levels over its period of intake. Since an immediate boost in testosterone is often desirable, athlete will commonly use HCG (human choronic gonadotropin) for a couple of weeks, and the continue treatment with Clomid.

Clomid is also effective as an anti-estrogen. Most athletes will suffer from an elevated estrogen level at the conclusion of a cycle. A high estrogen level combined with a low testosterone level puts an athlete in serious risk of developing gynocomastia. With the intake of Clomid, the athlete gets the dual effect of blocking out some of the effects of estrogen, while also increasing endogenous testosterone production.

Effective Dose: 1 - 2 tabs a day

Clomiphene Citrate (Clomid®)
Description:
by Bill Roberts - Clomid is the anti-estrogen of choice for improving recovery of natural testosterone production after a cycle, improving testosterone production of endurance athletes, and is also effective in reducing risk of gynecomastia during a cycle employing aromatizable steroids.

While it has been claimed that Clomid "stimulates" production of LH and therefore of testosterone, in fact Clomid's activity is achieved not by stimulation of the hypothalamus and pituitary, but by blocking their inhibition by estrogen.

Clomid is a mixed estrogen agonist/antagonist (activator/blocker) which, when bound to the estrogen receptor, puts it in a somewhat different conformation (shape) than does estradiol. The estrogen receptor requires binding of an estrogen or drug at its binding site and also the binding of any of several cofactors at different sites. Without the binding of the cofactor, the estrogen receptor is inactive. Different tissues use different cofactors. Some of these cofactors are able to bind to the estrogen receptor/Clomid complex, but others are blocked due to the change in shape. The result is that in some tissues Clomid acts as an antagonist -- the cofactor used in that tissue cannot bind and so the receptor remains inactive -- and in others Clomid acts as an agonist (activator), because the cofactors used in that tissue are able to bind.

Clomid is an effective antagonist in the hypothalamus and in breast tissue. It is an effective agonist in bone tissue, and for improving blood cholesterol.

Clomid also has the property of reducing the adverse effect of exercise-induced damage of muscle tissue. This is very significant for endurance athletes but is not very significant, if at all significant, with reasonable weight training. Clomid does not perceptibly affect gains of the weight trainer either favorably or adversely in my experience.

The drug seems to have estrogenic effects on mood, which can be beneficial (improving relationships with women by improving empathy) or can yield depression or PMS-like symptoms, but for most users there is no significant effect either way.

The claim that duration of intake should not exceed 10-14 days is incorrect. Clinical studies with male patients have been for periods of a year or longer. This error probably originates from the fact that, for use in women, due to the menstrual cycle there would obviously be no point in trying to stimulate ovulation all four weeks of the month. Thus, use in women is limited to 10-14 days. That limitation is not because of toxicity.

Clomid is in fact useful throughout a cycle if aromatizable drugs are being used. I do think however that to be conservative, one should use it no more than 2/3 of the time throughout the year or a little less.

Clomid (Clomiphene citrate)

Clomid 50 mg. tablets. Each clomid tablet contains 50 mg. clomiphene citrate. Clomid comes in packs of 30 tablets and is manufactured by Effik.

Common uses and directions for Clomid
Clomid is indicated for the treatment of ovulatory dysfunction in women desiring pregnancy. Impediments to achieving pregnancy must be excluded or adequately treated before beginning Clomid therapy.
The workup and treatment of candidates for Clomid therapy should be supervised by physicians experienced in management of gynecolic or endocrine disorders. Patients should be chosen for therapy with Clomid only after careful diagnostic evaluation.

Treatment of the selected patient should begin with a low dose, 50 mg. daily for 5 days. The dose should be increased only in those patients who do not ovulate in response to cyclic 50 mg. Clomid tablets.
Clomid, at recommended dosages, is generally well tolerated. Adverse reactions are usually mild and transient and most disappear promptly after treatment is discontinued.

Male athletes also find Clomid interesting. In men using Clomid, the elevation in both follicle stimulating hormone and (primarily) luteinizing hormone will cause natural testosterone production to increase. This effect is especially beneficial to the athlete at the conclusion of a steroid cycle when endogenous testosterone levels are depressed. If endogenous testosterone levels are not brought beck to normal, a dramatic loss in size and strength is likely to occur once the anabolics have been removed. Clomid can play a crucial role in preventing this crash in athletic performance.

More information about Clomid (Clomiphene citrate):

Clomid (Clomiphene citrate) additional information
Common uses
Clomid tablets, containing clomiphene citrate, is a non steroidal ovulatory stimulant.
Clomid is indicated for the treatment of ovulatory dysfunction in women desiring pregnancy.

Male athletes also find Clomid interesting. In men using Clomid, the elevation in both follicle stimulating hormone and (primarily) luteinizing hormone will cause natural testosterone production to increase. This effect is especially beneficial to the athlete at the conclusion of a steroid cycle when endogenous testosterone levels are depressed. If endogenous testosterone levels are not brought beck to normal, a dramatic loss in size and strength is likely to occur once the anabolics have been removed. Clomid can play a crucial role in preventing this crash in athletic performance.

Directions
Clomid comes as a tablet containing 50 mg. clomiphene citrate, to take by mouth. Impediments to achieving pregnancy must be excluded or adequately treated before beginning Clomid therapy.
The workup and treatment of candidates for Clomid therapy should be supervised by physicians experienced in management of gynecolic or endocrine disorders. Patients should be chosen for therapy with Clomid only after careful diagnostic evaluation.

Treatment of the selected patient should begin with a low dose, 50 mg. daily for 5 days. The dose should be increased only in those patients who do not ovulate in response to cyclic 50 mg. Clomid tablets.

For athletes using anabolic steroids, Clomid can normalize the testosterone level and the spermatogenesis (sperm development)within 10-14 days. For this reason Clomid is primarily taken after steroids are discontinued. At this time it is extremely important to bring the testosterone production to a normal level as quickly as possible so that the loss of strength and muscle mass is minimized.

50-100 mg./day seems is a sufficient dosage for athletes. Clomid is usually taken with fluids after meals. If several tablets are taken it is recomended that they be administered in equal doses distributed throughout the day. The duration of Clomid intake should not exceed 10 to 14 days. Most athlets begin with 100 mg./day taking one 50 mg. tablet every morning and evening after meals. After the fifth day the dosage is often reduced to only one 50 mg. tablet per day.

If you miss a dose, take it as soon as remembered if it is within an hour or so. If you do not remember until later, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Precautions
Blurring or other visual symptoms such as spots or flashes may occasionally occur during therapy with Clomid. These visual symptoms increase in incidence with increasing total dose or therapy duration and generally disappear within a few days or weeks after Clomid is discontinued. These visual symptoms may render such activites as driving a car or operating machinery more hazardous than usual, particularly under conditions of variable lighting.
If experiencing visual symptom, treatment should be discontinued and complete ophthalmologic evaluation performed.
There is an increased chance of multiple pregnancy, including bilateral tubal pregnancy and coexisting tubal and intrauterine pregnancy, when conception occurs in relation to Clomid therapy.
It is not known whether Clomid is excreted in human milk. Caution should be exercised if Clomid is administered to a nursing woman. In some individuals, Clomid may reduce lactation.
Prolonged use of Clomid may increase the risk of a borderline or invasive ovarian tumor

Possible side effects
Clomid at recommended dosages, is generally well tolerated. Adverse reactions usually have been mild and transient and most have disappeared promptly after treatment has been discontinued.
Side effects include ovarian enlargement, vasomotor flushes, abdominal-pelvic discomfort/distention/bloating, nausea and vomiting, breast discomfort, visual symptoms, headache and abnormal uterine bleeding. If you notice other effects not listed above, contact your doctor.

Overdose
If overdose of Clomid is suspected, contact your local poison control center or emergency room immediately. Toxic effects accompanying acute overdosage of Clomid have not been reported. Signs and symptoms of overdosage as a result of the use of more than the recommended dose during Clomid therapy include nausea, vomiting, vasomotor flushes, visual blurring, spots or flashes, scotomata, ovarian enlargement with pelvic or abdominal pain.

Additional information
Keep Clomid in a tightly closed container and out of reach of children. Store Clomid at room temperature and away from excess heat and moisture (not in the bathroom).

Note
The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, or other healthcare professional. It should not be construed to indicate that use of Clomid is safe, appropriate, or effective for you. Consult your healthcare professional before using Clomid.